Jan 31, 2009 Filed Under: House M.D. Comments Off

The team encounters a teenage boy who collapsed from severe pelvic pain after playing basketball. Tests reveal the boy has genetic mosaicism, or both male and female DNA, and the boy’s parents inform House and the team that the boy is unaware of his condition. They consciously chose a gender for him when he was born and raised him accordingly, never telling him about his unique condition. However, when his condition worsens and his life is threatened, the parents wonder whether they made the right decision. Meanwhile, Cuddy and Wilson suspect something is wrong with House when he starts acting way too nicely. When they discover the shocking answer, they must face the prospect that House may be changed forever in “The Softer Side” episode of HOUSE airing Monday, Feb. 16 (8:00-9:00 PM ET/ PT) on FOX. (HOU-516) (TV-14 D, L)

Cast: Hugh Laurie as Dr. Gregory House; Lisa Edelstein as Dr. Lisa Cuddy; Omar Epps as Dr. Eric Foreman; Robert Sean Leonard as Dr. James Wilson; Jennifer Morrison as Dr. Allison Cameron; Jesse Spencer as Dr. Robert Chase; Peter Jacobson as Dr. Chris Taub; Kal Penn as Dr. Lawrence Kutner; Olivia Wilde as Thirteen

Guest Cast: Dominic Scott Kay as Jackson; Julia Campbell as Melanie; Ben Reed as Joseph; Nick Puga as Ian; Fred Kronenberg as Doctor; Meagan Gordon as Young Woman; Nicole Cannon as Nurse Helen; Bobbin Bergstrom as Nurse